B 1: Investigation of bacterial ear infections and associated specimens

This document was withdrawn on 13 August 2024 following the publication of S 13: Painful and/or discharging ear. This is in line with the UK SMI strategy and in agreement with the UK SMI Steering Committee that technical UK SMIs will be replaced with the relevant syndromic document as they are published.

B 2: Investigation of bacterial eye infections

This document was withdrawn on 13 August 2024 following the publication of S 11: Red or painful eye. This is in line with the UK SMI strategy and in agreement with the UK SMI Steering Committee that technical UK SMIs will be replaced with the relevant syndromic document as they are published.

B 19: Investigation of sinus aspirate

This document was withdrawn on 30 December 2014. The contents of this document have been incorporated into B 5: Investigation of nasal samples.

B 23: Investigation of gastric aspirates and infection screen swabs from neonates

This document was withdrawn on 1 March 2012. The contents of this document will be incorporated into B 37: Investigation of blood cultures (for organisms other than Mycobacterium species).

B 30: Investigation of faecal specimens for enteric pathogens

This document was withdrawn on 27 May 2021 following the publication of UK SMI S7: gastroenteritis. This is in line with the UK SMI strategy and in agreement with the UK SMI Steering Committee that technical UK SMIs will be replaced with the relevant syndromic document as they are published.

B 37: Investigation of blood cultures (for organisms other than Mycobacterium species)

This document was withdrawn on 13 August 2024 following the publication of S 12: Sepsis and systemic or disseminated infections. This is in line with the UK SMI strategy and in agreement with the UK SMI Steering Committee that technical UK SMIs will be replaced with the relevant syndromic document as they are published.

B 47: Investigation of specimens for Legionella species

This document was recalled on 9 March 2012 due to an adjustment of reporting practice in England when testing patients for Legionella infection.

B 52: Investigation of intraocular fluids and corneal scrapings

This document was withdrawn on 30 December 2014. The contents of this document have been incorporated into B 2: Investigation of bacterial eye infections.

The UK SMI Clinical Guidance (G) documents were withdrawn between 2012 to 2016. The clinical background, differential diagnosis and appropriate investigation of the clinical conditions were available from other guidance producers and professional bodies.

G 1: Microbiological examination of CSFs, that may contain agents of spongiform encephalopathies

This document was withdrawn on 1 May 2012 as advice is available from the ACDP TSE Risk Management Subgroup (formerly TSE Working Group) page.

G 2: Microbiological investigation of patients with acute lymphadenopathy and fever

This document was withdrawn on 3 October 2016. This is due to the expansion of the Virology UK SMI templates to allow more information to be included in the documents and the work on the National User Manual.

G 3: Chlamydial zoonotic infections

This document was withdrawn on 3 October 2016. This is due to the expansion of the Virology UK SMI templates to allow more information to be included in the documents and the work on the National User Manual. The contents of this document have been incorporated into V 57: Chlamydial zoonotic infections.

G 4: Investigation of viral encephalitis and meningitis

This document was withdrawn on 3 October 2016. This is due to the expansion of the Virology UK SMI templates to allow more information to be included in the documents and the work on the National User Manual.

G 5: Investigation of hepatitis

This document was withdrawn on 3 October 2016. This is due to the expansion of the Virology UK SMI templates to allow more information to be included in the documents and the work on the National User Manual.

G 6: Investigation of vesicular rashes

This document was withdrawn on 3 October 2016. This is due to the expansion of the Virology UK SMI templates to allow more information to be included in the documents and the work on the National User Manual.

G 7: Investigation of red rash

This document was withdrawn on 3 October 2016. This is due to the expansion of the Virology UK SMI templates to allow more information to be included in the documents and the work on the National User Manual.

G 8: Respiratory viruses

This document was withdrawn on 3 October 2016. This is due to the expansion of the Virology UK SMI templates to allow more information to be included in the documents and the work on the National User Manual.

G 9: Investigation of specimens for ectoparasites

This document was withdrawn on 3 October 2016. This is due to the expansion of the Virology UK SMI templates to allow more information to be included in the documents and the work on the National User Manual.The contents of this document have been incorporated into B 61: Investigation of specimens for ectoparasites.

Q 3: European directive on in vitro diagnostic medical devices (IVD directive)

This document was withdrawn on 5 June 2017. Please refer to the EU In Vitro Diagnostic Device Regulation (IVDR) for information.

The UK SMI Protocol (P) documents were withdrawn between 2014 to 2016. The documents were not developed in accordance with the NICE accreditation standards in that each document was written and owned by experts with no external input.

 

P 1: Surveillance of Polio in the UK

The document is deemed outside the scope of UK SMIs and therefore was withdrawn on 22 July 2014.

P 2: Laboratory detection and reporting of bacteria with extended spectrum beta lactamases

This document was withdrawn on 4 August 2016. The contents of this document have been incorporated into B 59: Detection of Enterobacteriaceae producing extended spectrum β lactamases.

P 3: Recommendations for screening specimens for Corynebacterium species

This document was withdrawn on 10 September 2014. The contents of this document have been incorporated into B 9: Investigation of throat related specimens.

P 4: Guidance on the development and validation of diagnostic tests that depend on nucleic acid amplification and detection

This document was withdrawn on 7 January 2015 as it is no longer part of the UK Standards for Microbiology Investigations repository.

P 5: Investigation of toxoplasma infection in pregnancy

The document is deemed outside the scope of UK SMIs and therefore was withdrawn on 10 September 2014. For more information please refer to the Toxoplasma Reference Laboratory.

P 6: Detection of Neisseria gonorrhoeae using molecular methods

This document was withdrawn on 10 September 2014. Guidelines on this topic is now available with up to date information and replaces the content of P 6.

P 8: Laboratory detection and reporting of bacteria with carbapenem hydrolysing beta lactamases (carbapenemases)

This document was withdrawn on 13 September 2016. The contents of this document have been incorporated into B 60: Detection of bacteria with carbapenem hydrolysing β lactamases (carbapenemases).

TP 22: Nagler test

This document was withdrawn on 9 March 2015, as it is no longer possible to source the antitoxin needed to carry out the test procedure.

V 2: Gastroenteritis: sporadic cases

This document was withdrawn on 26 April 2012 as it has been superseded by Syndromic Algorithm S 7: Gastroenteritis and diarrhoea.

V 3: Gastroenteritis outbreaks

This document was withdrawn on 26 April 2012 as it has been superseded by Syndromic Algorithm S 7: Gastroenteritis and diarrhoea.

V 10: Blood borne virus testing in dialysis patients

This document was withdrawn on 19 December 2017 as guidance is available from Department of Health and the Renal Association.

V 12: Preparation of coated grids for electron microscopy

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 13: Electron microscopy floatation direct method

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 14: Electron microscopy differential centrifugation double spin method

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 15: Electron microscopy ammonium sulphate precipitation

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 16: Electron microscopy using solid phase immune electron microscopy

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 17: Isolation of Herpes Simplex virus associated with Herpes Genitalis

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 18: Complement fixation tests

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 21: Isolation of viruses associated with infections of the eye – keratoconjunctivitis

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 22: Immunofluorescence and isolation of viruses from respiratory samples

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 23: Isolation of human Herpes viruses (excluding Herpes genitalis)

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 24: Isolation of enteroviruses and parechoviruses

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 35: Investigation of cytomegalovirus infection by Roche Lightcycler PCR

This document was withdrawn in January 2012 as it is no longer fit for purpose.

V 39: Procedure for the care and propagation of cell cultures for virus isolation

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 45: Haemadsorption of viruses

This document was withdrawn on 10 September 2014 because these techniques are no longer commonly used in diagnostic virology laboratories.

V 47: Investigation of swine-lineage influenza A (H1N1) by PCR

This document was withdrawn on 17 April 2014.

V 49: Investigation of swine-lineage influenza A/H1N1 v using the quadriplex influenza A PCR assay with swine-lineage influenza A H1 and N1 assays

This document was withdrawn on 17 April 2014.

V 51: Investigation of swine-lineage influenza A/H1N1v using the swine-lineage influenza A H1 assay

These documents were withdrawn on 17 April 2014.